Description

Scotti et al reported the CITE score for evaluating a patient with mitral valve regurgitation who is COAPT-ineligible. This can help to identify a patient undergoing transcatheter edge-to-edge repair (TEET). The authors are from multiple institutions in Italy


COPAT is an acronym for a clinical trial (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation).

 

CITE is an acronym for COAPT-ineligible patient who underwent TEER.

 

Patient selection: mitral valve regurgitation, COAPT-ineligible patient who underwent TEER (transcatheter edge-to-edge repair)

 

Parameters:

(1) left ventricular impairment

(2) hemodynamic instability

(3) NYHA class

(4) peripheral arterial disease

(5) hemoglobin in g/dL, from 7 to 17

(6) atrial fibrillation

(7) serum BNP in pg/mL, from 0 to 2,000

 

line for hemoglobin =

= 14.286 - (0.84 * (hemoglobin))

 

line for serum BNP =

= (0.005 * (BNP))

 

Parameter

Finding

Points

left ventricular impairment

no

0

 

yes

3.32

hemodynamic instability

no

0

 

yes

2.52

NYHA class

I or II

0

 

III or IV

3.12

peripheral arterial disease

no

0

 

yes

2.17

atrial fibrillation

no

0

 

yes

1.45

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 27.69

 

value of X =

= (-0.005807 * ((score)^2)) - (0.1289 * (score)) + 2.309

 

probability of 2-year freedom from death or heart failure hospitalization =

= 1 / (1 + EXP((-1) * X))


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