Grading and Staging Chronic Hepatitis in Liver Biopsy

Purpose: To grade the severity of involvement and stage the degree of fibrosis in chronic hepatitis.

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Evaluation

Does the patient have chronic hepatitis?

Yes

Select the best answer for each finding

Portal inflammation

Piecemeal necrosis

Lobular inflammation

Hepatocellular damage

Fibrosis

Are regenerative nodules or other signs of cirrhosis present?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Grade of portal involvement

Grade of lobular involvement

Grade (severity of involvement)

Stage of fibrosis

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Clinical Diagnosis, Including Family History For Genetics
Laboratory Tests
Other Testing
Criteria For Diagnosis
Severity, Prognosis, Stage
- Algorithm of Bedossa and Poynard (METAVIR CSG) for Grading the Activity of Chronic Hepatitis C in a Liver Biopsy
- Discriminant Score of Bonacini et al for Predicting Cirrhosis in a Patient with Chronic Viral Hepatitis C
Complications
- Criteria of Schoeniger-Hekele and Mueller for Using CA19-9 and CA125 to Diagnose Severe Liver Fibrosis in a Pateint with Noncholestatic Liver Disease

Therapy

Selection

Monitoring

Disease Progression

Specialty

Gastroenterology
Infectious Diseases

Objective

severity
prognosis
stage

ICD-10

K73.9 - Chronic hepatitis, unspecified
K73.0 - Chronic persistent hepatitis, not elsewhere classified
K73.1 - Chronic lobular hepatitis, not elsewhere classified
K73.2 - Chronic active hepatitis, not elsewhere classified

Info

Purpose: To grade the severity of involvement and stage the degree of fibrosis in chronic hepatitis.

Specialty: Gastroenterology, Infectious Diseases

Objective: severity, prognosis, stage

ICD-10: K73.9, K73.0, K73.1, K73.2,

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