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Childhood Hodgkin International Prognostic Score (CHIPS) of Schwartz et al

Description

Schwartz et al reported the Childhood Hodgkin International Prognostic Score (CHIPS) for a pediatric patient with Hodgkin's disease. This can help in the decisions on how to manage the patient. The authors are from multiple institutions in the United States and members from the Children's Oncology Group.


Patient selection: pediatric patient with Hodgkin's disease (age < 22 years)

 

Parameters:

(1) fever (not elaborated)

(2) clinical stage

(3) large mediastinal mass (based on mediastinal tumor to thoracic diameter ratio)

(4) serum albumin in g/dL

 

Parameter

Finding

Points

fever

absent

0

 

present

1

clinical stage

Stage 1 to 3

0

 

Stage 4

1

large mediastinal mass

absent

0

 

present (ratio > 0.33)

1

serum albumin

>= 3.5 g/dL

0

 

< 3.5 g/dL

1

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 4

 

Score

4-Year Event-Free Survival

0

93.1%

1

88.5%

2

77.6%

3

69.2%

4

 

 


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