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Alkylator Score and Leukemia in Childhood Cancer Survivors

Purpose:

To identify a patient with a history of childhood cancer who is at increased risk for developing leukemia later in life.

Specialty:

Hematology Oncology

Objective:

criteria for diagnosis

ICD-10:

C90.1, C91, C92, C93, C94, C95

Description:

A patient who survives childhood cancer may be at increased risk for leukemia secondary to therapy with alkylating agents. Tucker et al developed an alkylator score to quantify a patient's exposure to alkylating agents. The authors are from multiple hospitals in North America and Europe participating in the Late Effects Study Group.

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