Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) Score of Extermann et al

Purpose: To identify an older adult who is at risk for severe adverse reaction to chemotherapy using the CRASH score of Extermann et al.

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Evaluation

Are you evaluating a patient prior to chemotherapy?

Yes

Age of the patient

years

Serum LDH

IU/L

Upper limit of the normal (ULN) reference range for serum LDH

IU/L

Diastolic blood pressure

mm Hg

Instrumental Activity of Daily Living (IADL)

Mini-Mental Status

Mini-Nutritional Assessment

Select an appropriate answer for each finding

Toxicity of chemotherapy regimen

ECOG performance

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Ratio of serum LDH to ULN

Score for hematologic toxicity

Risk of severe hematologic toxicity

Score for non-hematologic toxicity

Risk of severe non-hematologic toxicity

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Criteria For Diagnosis
- Advanced Stage Hodgkin Disease | Score for Treatment-Related Mortality (TRM)
Severity, Prognosis, Stage
- Tool for Predicting Acute Chemotherapy-Induced Nausea and Vomiting (CINV)
- Advanced Stage Hodgkin Disease | Score for Treatment-Related Mortality (TRM)
Complications

Therapy

Selection
- Anticipatory Nausea Index for Cancer Chemotherapy
Dosage Calculations
- Predicting Cycle One Serious Drug-Related Toxicity (SDRT) in Phase I Oncology Trial
Prevention
- Emetic Effect of Chemotherapeutic Agents

Monitoring

Response To Therapy
Adverse Effects
Drug Levels
- Predicting Cycle One Serious Drug-Related Toxicity (SDRT) in Phase I Oncology Trial
Overdose And Reversal
- Predicting Cycle One Serious Drug-Related Toxicity (SDRT) in Phase I Oncology Trial

Specialty

Hematology Oncology
Pharmacology, clinical

Objective

risk factors
response to therapy
adverse effects

ICD-10

T88.7 - Unspecified adverse effect of drug or medicament

Info

Purpose: To identify an older adult who is at risk for severe adverse reaction to chemotherapy using the CRASH score of Extermann et al.

Specialty: Hematology Oncology, Pharmacology, clinical

Objective: risk factors, response to therapy, adverse effects

ICD-10: T88.7,

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