A patient may develop the cerebral hyperperfusion syndrome following carotid artery revascularization.
Mechanism: arteries may become unable to autoregulate arterial blood flow in areas of chronic hypoperfusion
Types of carotid revascularization procedures associated with hyperperfusion:
(1) endarterectomy
(2) stent placement
Risk factors:
(1) severe and/or bilateral carotid artery stenosis
(2) previous stroke
(3) periprocedural hypertension
(4) poor collateral blood supply
Features of hyperperfusion:
(1) increased cerebral blood flow (increase > 100% over baseline)
(2) signs and symptoms ipsilateral to the treated artery including headache, eye or facial pain, vomiting, seizures, decreased level of consciousness or a focal neurological deficit
(3) exclusion of thromboembolism or stroke
Complications:
(1) bleeding with intracerebral or subarachnoid hemorrhage
(2) cerebral edema