Description

Oxygen at high partial pressures may be toxic to the central nervous system (CNS). This may occur in divers or in others exposed to high pressure environments. Recognition of mild or early symptoms can often allow preventive steps, but the full blown syndrome can be life-threatening when considering the environments in which it occurs.


 

Conditions favoring its occurrence:

(1) elevated partial pressure of oxygen to > 1.6 atmospheres (rare if < 1.4 atmospheres). This is encountered only in divers or someone in a pressurized environment.

(2) elevation in carbon dioxide (from inadequate ventilation during heavy exertion, failure of carbon dioxide scrubbing, or presence of CO2 in breathing mixture)

(3) increased exertion or metabolic function. This may include shivering, strenuous exercise, thyrotoxicosis, stimulant overdosage.

(4) increased time of exposure

 

Symptoms (make the mnemonic VENTIDC):

(1) visual symptoms, including tunnel or blurred vision

(2) ear symptoms, with tinnitus (roaring, bells ringing, machinery-like)

(3) nausea or spasmotic vomiting

(4) twitching or tingling, affecting muscles in the face, lips or extremities

(5) irritability, plus confusion, agitation and anxiety

(6) dizziness, plus clumsiness, incoordination or unusual fatigue

(7) convulsions, and possibly loss of consciousness

 

where:

• DIVE CNS might be another mnemonic, with S for spasms replacing T for twitching and tingling).

 


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