The Centers for Disease Control and Prevention has developed a guideline for preexposure prophylaxis (PrEP) to prevent spread of HIV to certain high risk populations. One group involves males who have sex with males (MSM).


A candidate for HIV preexposure prophylaxis – all of the following

(1) adult male who has sex with males

(2) without established HIV infection or acute HIV infection

(3) any male sex partners in the past 6 months

(4) not in a monogamous partnership with an HIV-negative man (confirmed by recent testing)

(5) one or more of the following:

(5a) any sexually transmitted disease in past 6 months

(5b) ongoing sexual relationship with an HIV-positive male

(5c) any anal sex (insertive or receptive) without the use of a condom I the past 6 months



• An adolescent male can be sexually active and so may be at risk. However, providing prophylaxis to this population may require involvement of the patient’s parents or guardians.


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