Criteria for a bacteremia/fungemia shock event, with all of the following:
(1) one or more blood specimens positive by culture or positive molecular methods
(2) isolation of a presumed pathogen (exclusion of contaminants)
(3) new vasopressor (norepinephrine, dopamine, epinephrine, phenylephrine, vasopressin) started within a time window from 2 days before to 2 days after the positive blood specimen
A new vasopressor:
(1) does not include one given in the operating room or during a procedure
(2) should not have been administered within the 24 hours prior to first dose
The onset is classified as community- or hospital-onset.
(1) community onset: while in the community or less than 48 hours after hospital admission
(2) hospital onset: more than 48 hours after hospital admission