Criteria 1: organism isolated from culture of purulent material from tissues or oral cavity
Criteria 2 - at least one of the following:
(1) abscess or other evidence of oral cavity infection seen on direct examination
(2) abscess or other evidence of oral cavity infection seen during surgery
(3) abscess or other evidence of oral cavity infection seen by histopathologic examination
Criteria 3 - both of the following:
(1) at least one of the following:
(1a) abscess
(1b) ulceration
(1c) raised white patches on inflamed mucosa
(1d) plaques on oral mucosa
(2) at least one of the following:
(2a) organisms seen on Gram stain
(2b) positive potassium hydroxide (KOH) stain
(2c) positive antigen test on oral secretions
(2d) multinucleated giant cells seen on microscopic examination of mucosal scrapings
(2e) diagnostic single IgM antibody titer for pathogen
(2f) fourfold increase in IgG antibody titer in paired serum samples for pathogen
(2g) physician's diagnosis and treatment with topical or oral antifungal therapy
