Dingli et al developed a simple scored based on the complete blood count (CBC) for evaluating a patient with agnogenic myeloid metaplasia. This can help to identify patients who may benefit from more aggressive management. The authors are from the Mayo Clinic.
Parameters:
(1) hemoglobin in g/dL
(2) white blood cell (WBC) count
(3) platelet count per microliter
Parameter
Finding
Points
hemoglobin
>= 10 g/dL
0
< 10 g/dL
1
WBC count
< 4,000 per µL
1
4,000 to 10,000 per µL
0
> 10,000 per µL
1
platelet count
< 100,000 per µL
1
>= 100,000 per µL
0
where:
• The cutoff for hemoglobin was not adjusted for gender.
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the lower the median survival.
Total Score
Median Survival
0
155 months
1
69 months
2 or 3
24 months
Additional risk factors associated with reduced survival:
(1) presence of constitutional symptoms (night sweats, unexplained fever > 100°F, unintended weight loss > 10% of baseline body weight)
(2) hepatomegaly
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