Description

Retroperitoneal fibrosis may be associated with a number of conditions. Identifying the cause is important for determining the appropriate management.


 

Drugs:

(1) beta blocking agents

(2) chronic use of NSAID analgesics

(3) hydralazine

(4) methyldopa

(5) ergotamine

(6) methysergide

(7) pergolide

(8) bromocriptine

 

Radiation therapy to the abdomen or retroperitoneum

 

Infection:

(1) histoplasmosis

(2) tuberculosis

(3) actinomycosis

 

Major surgery to the pelvis or retroperitoneum:

 

Malignancy or cellular proliferations:

(1) Hodgkin's disease

(2) non-Hodgkin's malignant lymphoma

(3) sarcoma

(4) carcinoid tumor

(5) carcinoma of the stomach or colon

(6) carcinoma of the pancreas

(7) carcinoma of the prostate

(8) breast carcinoma

(9) histiocytosis

 

Autoimmune disease

 

Trauma to the abdomen or retroperitoneum

 

Amyloidosis

 

If no cause is identified, then it is termed idiopathic.

 


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