Congenital complete atrioventricular block (CCAVB) is an uncommon but potentially serious cardiac condition.


Conditions associated with CCAVB:

(1) structural cardiac malformations

(2) maternal autoimmune disease (usually SLE) with autoantibodies to SS-A/Ro and/or SS-B/La ribonucleoproteins

(3) genetic mutation in the SCN5A or NKX2.5 pathways (which may have a familial pattern of inheritance)


Structural cardiac malformations associated with CCAVB include:

(1) anomalies of great vessel development (correct transposition, etc)

(2) univentricular heart


Cardiac pacing can be used to restore cardiac function in infected infants.


To read more or access our algorithms and calculators, please log in or register.