Brown's syndrome may occur due to a wide range of conditions.

Mechanism: disorder of the superior oblique muscle, tendon or surrounding tissues


Brown's syndrome may be:

(1) congenital

(2) acquired



(1) orbital trauma, including animal bite

(2) peri-ocular surgery, including glaucoma implant

(3) peribulbar anesthesia

(4) blepharoplasty with fat removal

(5) lichen sclerosus et atrophicus

(6) postpartum

(7) neoplasm in superior nasal orbit

(8) thyroid disease

(9) Hurler-Scheie syndrome

(10) connective tissue disorder (rheumatoid arthritis, systemic lupus erythematosus, other)

(11) myositis or tenosynovitis affecting the superior oblique muscle

(12) sinusitis

(13) trochleitis

(14) other causes of periorbital inflammation and/or fibrosis

(15) idiopathic

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