Ichthyosis may be hereditary or acquired. Acquired ichthyosis can be causes by a range of conditions.
Ichthyosis is a thickened, dry, scaling of the skin that is typically symmetrical.
Conditions associated with acquired ichthyosis:
(1) paraneoplastic ichthyosis
(2) endocrine disorders (diabetes mellitus; hypothyroidism; autoimmune thyroiditis)
(3) drugs (clofazimine; statins; allopurinol; acitretin; EGFR inhibitors; BRAF inhibitors)
(4) nutritional deficiencies
(5) chronic renal disease
(6) chronic liver disease
(7) immune disorders (SLE; Crohn's disease; celiac disease; sarcoidosis)
(8) infections (tuberculosis; AIDS)
Some patients may have overlapping causes.
Correction of the underlying will often result in regression of the ichthyosis.
