Therapeutic apheresis has been tried in many difficult-to-treat conditions. The role of therapeutic apheresis can be classified based on its effectiveness in a given clinical situation.
Parameters:
(1) accepted therapeutic role (with or without other modes of treatment)
(2) other consideration
Accepted Therapeutic Role
Other Considerations
Category
first-line
NA
I
second-line
NA
II
not established
decision-making should be individualized
III
none
may be ineffective or harmful
IV
For Category III and IV indications:
(1) The rationale needs to be carefully documented.
(2) Informed consent should be carefully documented.
For Category IV indications:
(1) These may not be covered by insurance.
(2) They may be associated with liability.
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