Castleman Disease Symptoms | Medical Algorithm

Are you evaluating a patient for multicentric Castleman's Disease?

Yes

Does the patient have?

• systemic constituional findings (weight loss, night sweats, fever, fatigue)?

Yes

• anemia?

Yes

• generalized lymphadenopathy?

Yes

• splenomegaly and/or hepatomegaly?

Yes

• a cutaneous rash?

Yes

• a vasculitis?

Yes

• neurologic changes (seizures, peripheral neuropathy, other)?

Yes

• peripheral edema?

Yes

• effusions?

Yes

• TTP?

Yes

• autoimmune hemolytic anemia?

Yes

Does the patient have?

• polyclonal hypergammaglobulinemia?

Yes

• hypoalbuminemia?

Yes

• elevated C-reactive protein (CRP)?

Yes

• elevated IL-6 and other cytokines?

Yes

• elevated erythrocyte sedimentation rate (ESR)?

Yes

• a herpesvirus-8 viral load (HHV-8, Kaposi-sarcoma associated herpesvirus, KSHV)?

Yes

Has the patient developed?

• non-Hodgkin's malignant lymphoma?

Yes

• amyloidosis?

Yes

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Data complete?

Evaluation appropriate?

Number of common clinical findings present

Number of variable findings present

Number of laboratory findings present

Number of complications seen with multicentric Castleman's disease

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Evaluation

Results

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Interpretation and Description

References

Specialty

Objective

ICD-10

Multicentric Castleman's Syndrome Clinical & Laboratory Findings

Purpose: To evaluate a patient for clinical and laboratory findings associated with multicentric Castleman's disease.

Evaluation

Results

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Interpretation and Description

References

Specialty

Objective

ICD-10