Case Definition for Crimean Congo Hemorrhagic Fever (CCHF)

Suspected case - both of the following:

(1) fever, myalgia, malaise and diarrhea

(2) one of the following:

(2a) residence in a CCHF endemic region

(2b) travel to a CCHF endemic region

NOTE: Since it can be spread as a nosocomial infection, contact with an infected patient can be added.

Probable case - both of the following:

(1) criteria for suspected case

(2) 2 or more of the following:

(2a) leukopenia

(2b) thrombocytopenia

(2c) elevated AST, ALT or LDH

Confirmed case - both of the following:

(1) criteria for suspected case

(2) evidence of CCHF virus with one or more of the following:

(2a) IgM antibody to CCHFV in serum

(2b) positive PCR for CCHFV in blood or body fluid

NOTE: The presence of either marker of CCHFV was added as a probable case if suspected criteria not met.