CART Models of Speiser et al for a Patient with Acetaminophen-Induced Acute Liver Failure: Post-Admission Model Based on Variables from King's College Criteria

Patient selection: acetaminophen-induced acute liver failure

Parameters from post-admission (days 3 to 7):

(1) coma grade (from I to IV)

(2) serum creatinine in mg/dL

Arterial blood pH and INR are variables from the King's College criteria but ares not used in this CART model.

where:

• The cutoffs for each variable are different from those used for the King's College Criteria (KCC).

• The absence of coma is not included in the CART tree but added to the implementation.

Performance:

• The area under the ROC curve was 0.72 to 0.81.