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Description

Petrilli et al evaluated patients with COVID-19 who required critical care. They identified risk factors that can help to identify a patient who may require more aggressive management. The authors are from New York University in New York City.


Patient selection: patient admitted to hospital with COVID-19

 

More important risk factors for critical illness:

(1) oxygen saturation < 88% (odds ratio 7.0)

(2) first plasma D-Dimer > 2,500 in ng/mL (odds ratio 6.9)

(3) first serum ferritin > 2,500 in ng/mL (odds ratio 6.9)

(4) first serum C-reactive protein > 200 mg/L (odds ratio 5.8)

 

Parameters for CART analysis:

(1) peripheral capillary oxygen saturation (SpO2) in percent

(2) first serum procalcitonin (ProCal) in ng/mL

(3) first serum troponin in ng/mL

(4) first serum C-reactive protein (CRP) in mg/L

(5) age in years

(6) history of hypertension (HT)

 

SpO2

ProCal

Troponin

CRP

Years

HT

Critical

< 88%

NA

NA

NA

NA

NA

82%

>= 88%

> 0.5

< 0.1

> 200

NA

NA

70%

>= 88%

> 0.5

< 0.1

<= 200

NA

NA

43%

>= 88%

> 0.5

>= 0.1

NA

NA

NA

88%

>= 93%

<= 0.5

NA

NA

NA

NA

25%

88 - 92%

<= 0.5

NA

NA

<= 64

NA

34%

88 - 92%

<= 0.5

NA

NA

> 64

No

65%

88 - 92%

<= 0.5

NA

NA

> 64

Yes

48%

 


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