Guidelines for Diagnosis of Cardiac Sarcoidosis

Have non-caseating epithelioid granulomas been identified on histologic examination of a cardiac biopsy?

Has sarcoidosis been identified on histology of an extracardiac site?

Is there abnormal wall motion, regional wall thinning or dilatation of the left ventricle?

Does myocardial scintigraphy show a perfusion defect or an abnormal marker accumulation?

Is there abnormal intracardiac pressure, low cardiac output, or depressed ejection fraction of the left ventricle?

Is there moderate to severe interstitial fibrosis or mononuclear cellular infiltration?

• complete right bundle branch block?

• left-axis deviation?

• atrioventricular block?

• ventricular tachycardia?

• premature ventricular contraction?

• abnormal Q change?

• ST-T change?