Patient selection: renal cell carcinoma, undergoing surgical resection
Parameters:
(1) serum CRP in mg/L (C)
(2) serum albumin in g/dL (A)
(3) absolute neutrophil count per microliter (N)
(4) absolute lymphocyte count per microliter (L)
(5) platelet count per microliter (P)
(6) hemoglobin in g/dL (H)
(7) gender
CRP to albumin ratio =
= (CRP) / (albumin)
neutrophil to lymphocyte ratio =
= ANC / ALC
platelet to hemoglobin ratio =
= ((platelet count) / 10000) / (hemoglobin)
|
Parameter
|
Finding
|
Points
|
|
CRP to albumin ratio
|
< 1.5
|
0
|
|
|
>= 1.5
|
1
|
|
neutrophil to lymphocyte ratio
|
< 2.8
|
0
|
|
|
>= 2.8
|
1
|
|
platelet to hemoglobin ratio
|
< 2.1 and male
|
0
|
|
|
>= 2.1 and male
|
1
|
|
|
< 2.3 and female
|
0
|
|
|
>= 2.3 and female
|
1
|
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
|
Total Score
|
5-Year Cancer Specific Survival
|
|
0
|
97%
|
|
1
|
89%
|
|
2
|
67%
|
|
3
|
36%
|
Performance:
• The area under the ROC curve is 0.79.
