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Calculating the Lod Score from Family Data with Phase Unknown Meioses

Specialty:

Genetics

Objective:

ICD-10:

Description:

If offspring of a parent inherit one of two genotypic combinations but the phase of meiosis is unknown, then either one or the other is recombinant while the other is nonrecombinant. The calculation of the lod score in this situation is similar to that for phase known meiosis, except for the additional possibility that alleles were in repulsion.

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