C-Reactive Protein (CRP) to Albumin Ratio and Prognosis in a Patient with Operable Squamous Cell Carcinoma of the Esophagus

 

Patient selection: operable squamous cell carcinoma of the esophagus

 

Outcome: 5-year overall survival

 

Parameters on preoperative blood samples:

(1) serum CRP in mg/L

(2) serum albumin in g/L

 

Alternatively mg/dL and g/dL can be used respectively. The units mg and gram are not adjusted for.

 

ratio of CRP to albumin =

= (CRP) / (albumin)

 

Interpretation:

• The lower the CRP and the higher the serum albumin the better the prognosis. This is associated with a small rato.

• Patients with a ratio > 0.50 had an odds ratio of 2.4 for mortality compared to patients with a ratio <= 0.5.

 

Additional factors associated with increased mortality:

(1) lymph node metastases

(2) vascular invasion