A diabetic patient may develop cutaneous bullae.


Clinical features:

(1) There is the sudden appearance of one or more tense blisters or bullae.

(2) They usually appear on the acral regions (fingers, hands, forearms, toes, feet, lower legs).

(3) The blisters are full of clear fluid (unless secondarily infected).

(4) The lesions are asymptomatic other than for the swelling.

(4) The bullae resolve in a few weeks without scarring.

(5) The lesions may be recurrent.


The bullae may be intraepidermal or subepidermal.


Differential diagnosis:

(1) burn injury

(2) cellulitis

(3) other bullous disorders


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