Bronchiectasis may develop in a patient with one or more predisposing conditions.


Infectious diseases:

(1) Pseudomonas species

(2) Hemophilus influenzae

(3) Aspergillus species

(4) adenovirus

(5) measles virus

(6) influenza virus

(7) HIV

(8) Mycobacterial species (M. tuberculosis, M. avium-intracellulare)


Autoimmune disorders:

(1) rheumatoid arthritis (RA)

(2) systemic lupus erythematosus (SLE)

(3) Sjogren's syndrome

(4) relapsing polychronditis

(5) ulcerative colitis

(6) Crohn's disease


Hereditary disorders:

(1) cystic fibrosis

(2) yellow nail syndrome

(3) primary ciliary dyskinesia

(4) alpha-1 antitrypsin deficiency (AAT)

(5) Mounier-Kuhn syndrome (tracheobronchomegaly)

(6) William-Campbell syndrome (cartilage deficiency)

(7) pulmonary sequestration

(8) Marfan's syndrome

(9) primary hypogammaglobulinemia


Toxic inhalations:

(1) chlorine gas


Secondary causes

(1) recurrent aspiration (heroin overdose, etc)

(2) foreign body aspiration

(3) secondary ciliary dyskinesias (Young's syndrome)

(4) secondary hypogammaglobulinemia (CLL, other)

(5) secondary immunodeficiency (organ transplant, etc)


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