Description

Mendiondo et al developed a screening test for Alzheimer’s disease that is intended to be brief and easily administered. This can help identify patients who may benefit from a more complete evaluation. The authors are from the University of Kentucky.


 

Patient selection: age > 60 years of age

 

Parameters:

(1) recall of 3 items (apple, table, penny)

(2) number of animals recalled in 30 seconds

(3) today’s date

(4) spelling the word “WORLD” backwards

Parameter

Finding

Points

3 item recall

all 3 items

3

 

2 items

2

 

1 item

1

 

none

0

number of animals

 

<number>

today’s date

correct

1

 

incorrect

0

spelling backward

all 5 letters

5

 

4 letters

4

 

3 letters

3

 

2 letters

2

 

1 letter

1

 

none

0

 

BAS =

= (3.03 * (points for recall)) + (0.67 * (number of animals named)) + (4.75 * (points for today’s date)) + (2.01 * (points for spelling backwards))

 

Interpretation:

• minimum score: 0

• maximum score: varies with the number of animals recalled, but probably around 37.29 (if 20 animals recalled)

• The performance varies with the cutoff values used and the reference method. Using a cutoff of <= 26 to indicate the Alzheimer’s disease and a CERAD validation group, the sensitivity was 99% and specificity was 87%.

 


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