Description

One of the skeletal manifestations of Gaucher disease is bone crises.


 

Synononym: pseudo-osteomyelitis

 

Patient selection: Gaucher disease

 

Clinical features of a bone crisis:

(1) acute onset of severe skeletal pain

(2) fever

(3) leukocytosis

(4) elevated erythrocyte sedimentation rate (ESR) or C-reactive protein

(5) negative blood and bone cultures

 

Imaging findings:

(1) periosteal elevation on routine X-ray

(2) photopenia on radionuclide bone scan

(3) increased T2-weighted signal on MRI

 


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