One of the skeletal manifestations of Gaucher disease is bone crises.
Patient selection: Gaucher disease
Clinical features of a bone crisis:
(1) acute onset of severe skeletal pain
(4) elevated erythrocyte sedimentation rate (ESR) or C-reactive protein
(5) negative blood and bone cultures
(1) periosteal elevation on routine X-ray
(2) photopenia on radionuclide bone scan
(3) increased T2-weighted signal on MRI
To read more or access our algorithms and calculators, please log in or register.