Tacconelli et al reported several scores for predicting mortality in a patient with sepsis, with scores for 14-day and 6-month mortality. Each temporal view has a quick and a full model. The authors are from multiple institutions in Germany and Italy participating in the DZIF BLOOMY study group.
BLOOMY is an acronym for Bloodstream Infection due to multidrug-resistant Organisms: Multicenter Study on Risk Factors and Clinical Outcomes.
Patient selection: hospitalized adult with >= 1 blood culture positive for Staphylococcus aureus, Enterococcus species, E. coli, Klebsiella species, Enterobacter species, Pseudomonas aeruginosa and Acinetobacter baumannii.
Outcome: 6-month mortality
Parameters:
(1) age in years
(2) malignancy with metastases
(3) platelet count per microliter
(4) serum CRP in mg/dL
(5) white blood cell count per microliter
Parameter
Finding
Points
age in years
< 80 years
0
>= 80 years
1
malignancy with metastases
no
0
yes
2
platelet count
> 150,000 per µL
0
50,001 to 150,000
1
<= 50,000 per µL
2
CRP
< 5 mg/dL
0
5 to 19.99 mg/dL
1
>= 20 mg/dL
2
WBC count
< 8,000 per µL
0
8,000 to 12,999 per µL
1
>= 13,000 per µL
2
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 9
Score
Mortality Rate in Derivation Cohort
Mortality Rate in Validation Cohort
0 or 1
12.8%
10.5%
2 or 3
27.1%
27.1%
>= 4
58.7%
59.8%
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