Tacconelli et al reported several scores for predicting mortality in a patient with sepsis, with scores for 14-day and 6-month mortality. Each temporal view has a quick and a full model. The authors are from multiple institutions in Germany and Italy participating in the DZIF BLOOMY study group.
BLOOMY is an acronym for Bloodstream Infection due to multidrug-resistant Organisms: Multicenter Study on Risk Factors and Clinical Outcomes.
Patient selection: hospitalized adult with >= 1 blood culture positive for Staphylococcus aureus, Enterococcus species, E. coli, Klebsiella species, Enterobacter species, Pseudomonas aeruginosa and Acinetobacter baumannii.
Outcome: 14-day mortality
Parameters:
(1) age in years
(2) hypotension on day 3 after onset
(3) mental status on day 3 after onset
Parameter
Finding
Points
age in years
< 40 years
0
40 to 79 years
2
>= 80 years
3
hypotension
no
0
yes
2
mental status
normal
0
disoriented
2
stupor
3
coma
4
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 9
• The higher the score the greater the risk of mortality.
Score
Mortality Derivation
Mortality Validation
0 to 3
2.7%
6%
4 to 6
16.5%
39%
>= 7
52.5%
50%
Performance:
• The area under the ROC curve is 0.83.
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