Serebruany and Atar developed the BleedScore for classifying bleeding events during clinical trials of antiplatelet and antithrombotic agents. The authors are from John Hopkins University and the University of Oslo.
Severity categories:
(1) superficial
(2) internal
(3) alarming
Superficial bleeding:
(1) easy bruising
(2) bleeding from small cuts
(3) petechiae
(4) ecchymosis
Internal bleeding:
(1) hematoma
(2) epistaxis
(3) blood loss from mouth
(4) blood loss from vagina
(5) melena
(6) eye bleeding
(7) hematuria
(8) hematemesis
Alarming bleeding:
(1) transfusion needed
(2) intracranial hemorrhage
(3) life-threatening bleeding
Parameter |
Finding |
Points |
---|---|---|
easy bruisability |
absent |
0 |
|
present |
1 |
bleeding from small cuts |
absent |
0 |
|
present |
1 |
petechiae |
absent |
0 |
|
present |
1 |
ecchymosis |
absent |
0 |
|
present |
1 |
hematoma |
absent |
0 |
|
present |
3 |
epistaxis |
absent |
0 |
|
present |
3 |
blood loss from mouth |
absent |
0 |
|
present |
3 |
blood loss from vagina |
absent |
0 |
|
present |
3 |
melena |
absent |
0 |
|
present |
3 |
eye bleeding |
absent |
0 |
|
present |
3 |
hematuria |
absent |
0 |
|
present |
3 |
hematemesis |
absent |
0 |
|
present |
3 |
transfusion necessary |
absent |
0 |
|
present |
6 |
intracranial bleeding |
absent |
0 |
|
present |
6 |
life threatening hemorrhage |
absent |
0 |
|
present |
6 |
where:
• A life threatening hemorrhage that requires transfusion might be scored as 12 or 6.
subscore for superficial bleeding =
= SUM(points for all 4 parameters)
subscore for internal bleeding =
= SUM(points for all 8 parameters)
subscore for alarming bleeding =
= SUM(points for all 3 parameters)
total score =
= SUM(points for all 15 items)
Interpretation:
• minimum total score: 0
• maximum total score: 46 for a female, 43 for a male
• The higher the score the more severe the bleeding.
Limitations:
• Some conditions such as epistaxis may range from mild to severe.
• Whether the bleeding can be controlled is often clinically important.
Purpose: To use the BleedScore of Serebruany and Atar to evaluate bleeding in a patient being treated with an antiplatelet or antithrombotic agent.
Specialty: Hematology Oncology, Clinical Laboratory, Pharmacology, clinical
ICD-10: R58,