Groups given selective beta-2 agonists to provide bronchodilation:
(1) bronchial asthma
(2) chronic obstructive pulmonary disease
Cardiovascular effects of a beta-adrenergic agonist may include:
(1) sinus tachycardia, atrial fibrillation, ventricular tachycardia, or other tachyarrhythmia
(2) acute myocardial infarction
(3) congestive heart failure
(4) syncope
(5) cardiac arrest or sudden cardiac death
Risk factors for adverse cardiovascular effect:
(1) high dose of the beta-agonist
(2) frequent dosing of the beta-agonist
(3) underlying cardiovascular disease
(4) interacting drugs that interfere with the beta-agonist metabolism or otherwise heighten its response
(5) exposure to other stimulants (excessive thyroid hormone, amphetamines, cocaine, etc)
(6) new user
