Basingstoke Models for Survival After Resection of Hepatic Metastases from a Colorectal Cancer: Preoperative Score

Description

Rees et al reported scores for predicting survival following resection of hepatic metastases from a colorectal cancer. One score gives a preoperative assessment and the second a postoperative one. The authors are from North Hampshire Hospital in Basingstoke and Imperial College London.

Patient selection: resectable hepatic metastases from a colorectal cancer

Outcome: various measures of cancer-specific survival

Parameters:

(1) lymph nodes status of primary tumor (N)

(2) differentiation of primary colorectal cancer

(3) CEA level at time of hepatectomy in ng/mL

(4) number of hepatic metastases

(5) largest tumor diameter in cm

(6) extrahepatic metastatic disease

Parameter	Finding	Points
lymph node status	negative (N0)	0
	positive (N1 or N2)	2
differentiation	well-differentiated	0
	moderately differentiated	3
	poorly differentiated	5
CEA level	< 6 ng/mL	0
	6 to 60 ng/mL	2
	> 60 ng/mL	3
number of hepatic metastases	1 to 3	0
	>= 4	4
largest tumor diameter	< 5 cm	0
	5 to 10 cm	2
	> 10 cm	8
extrahepatic metastases	no	0
	yes	7

total score =

= SUM(points for all parameters)

Interpretation:

• minimum score: 0

• maximum score: 29

• The higher the score the worse the survival.

Total Score	5-Year Cancer Specific Survival	Median Survival in Years
0	66	7.5
5	51	5.0
10	35	3.4
15	21	2.2
20	12	1.4
25	5	1.0
30	2	0.6

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Basingstoke Models for Survival After Resection of Hepatic Metastases from a Colorectal Cancer: Preoperative Score

Description

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