Base Excess and Platelet (BEP) Score of Alves et al for a Pediatric Patient with Meningococcemia

 

Patient selection: "child" (mean age 3.25 +/- 0.59 years, or 2.1 to 4.4) with meningococcemia with fever, hemorrhagic rash, sepsis or septic shock

 

Parameters:

(1) base excess in mmol/L (usually a negative number since the patients usually have a base deficit)

(2) platelet count in 10^9/L

 

X =

= (0.18909 * (base excess)) + (0.01015 * (platelet count)) + 3.07861

 

probability of mortality = BEP score =

= 1 / (1 + EXP(X))

 

Interpretation:

• The score was considered positive if the BEP score was > 0.3.

 

Limitations:

• The actual derivation of the logistic regression is not reported.

• Usually the probability equation is = 1 / (1 + EXP((-1) * X)), which means that the true formula for X should be (-1) times the value given above.