For a patient with Barrett's specialized metaplasia of the esophagus, a number of clinical factors may affect the risk for developing adenocarcinoma. Patients with multiple high risk factors benefit from closer surveillance.
Parameter |
Low Risk |
Intermediate Risk |
High Risk |
age in years |
< 40 |
40 – 45 |
> 45 |
gender |
female |
|
male |
length of Barrett's metaplasia in cm |
< 3 cm |
3 – 8 cm |
> 8 cm |
reflux |
mild, < 1 per week |
severe <= 3 times per week; moderate; mild >= 1 per week |
severe, > 3 times per week |
chronicity in years |
< 1 years |
1 – 10 years |
> 10 years |
race |
black |
|
white |
body weight |
normal weight |
|
obese |
family history |
none |
|
gastric cancer |
drug therapy |
NSAIDS |
|
nitrates, theophylline, anticholinergics, benzodiazepines |
H. pylori disease |
present |
|
absent |
smoking |
none |
light smoker |
heavy smoker |
mucosal damage |
intact |
|
ulceration or stricture in metaplastic epithelium |
from Panel 1, page 2080
Purpose: To evaluate the number of risk factors for developing adenocarcinoma in a patient with Barrett's metaplasia in the esophagus.
Specialty: Hematology Oncology, Surgery, general, Gastroenterology
Objective: risk factors
ICD-10: K22.1, K22.7,