Description

Avascular osteonecrosis is a potential complication of sickle cell disease. It is an independent risk factor for acute care utilization.


Patient selection: sickle cell disease (SCD)

 

More common sites:

(1) hip (femoral head and/or acetabulum)

(2) proximal humerus

 

Other sites:

(1) facial bones, including at the TMJ

(2) scaphoid

(3) talar neck

 

Risk factors:

(1) multiple vaso-occlusive crises

(2) history of previous osteonecrosis

(3) high-normal or elevated platelet count


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