The American Society of Clinical Oncology (ASCO) has reviewed complications associated with immune checkpoint inhibitor therapy.
Patient selection: inflammatory arthritis following therapy with immune checkpoint inhibitor
Parameters:
(1) clinical findings
(2) pain
(3) impact
|
Clinical Findings
|
Pain
|
Impact
|
Grade
|
|
none
|
none
|
none
|
G0
|
|
inflammation, erythema or joint swelling
|
mild
|
mild
|
G1
|
|
inflammation, erythema or joint swelling
|
moderate
|
limits instrumental ADL
|
G2
|
|
inflammation, erythema or joint swelling; irreversible joint damage
|
severe
|
disabling; limits self-care ADL
|
G3/G4
|
The diagnosis requires exclusion of other diagnoses that can explain the findings.
