The American Society of Clinical Oncology (ASCO) has reviewed complications associated with immune checkpoint inhibitor therapy.
Patient selection: autonomic neuropathy following therapy with an immune checkpoint inhibitor
Parameters:
(1) signs and symptoms
(2) functional status
(3) intervention
|
Signs and Symptoms
|
Functional Status
|
Intervention
|
Grade
|
|
mild
|
no interference
|
none
|
G1
|
|
moderate, concerning to patient
|
some interference
|
observe, start prednisone
|
G2
|
|
severe
|
limited self-care
|
admit to hospital
|
G3/G4
|
The diagnosis requires exclusion of other causes of autonomic neuropathy.
