A patient with a paraproteinemia may have an artifactual hyperbilirubinemia.
Method: Roche Hitachi serum total bilirubin
Cause of interference: protein precipitation with turbidity
Clues that there may be a problem with the assay:
(1) The patient is not jaundiced.
(2) The specimen is not icteric.
(3) A much lower value for the total bilirubin is given by an alternative method.
(4) The direct bilirubin assay is unaffected.
If the patient is jaundiced or the specimen icteric then the problem might go unnoticed.
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Specialty: Clinical Laboratory, Obstetrics & Gynecology, Cardiology, Emergency Medicine, Critical Care
Objective: laboratory tests, complications
ICD-10: D89.2,
