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Artifacts from Tissue Being Over-Decalcified

Specialty:

Clinical Laboratory

Objective:

ICD-10:

Description:

Bone and other ossified tissue must have calcium removed for the tissue to be soft enough to section. This is achieved by placing the tissue in a decalcification solution based around an acid. Over-decalcification of tissue prior to processing can result in a number of artifacts in the final sections.

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