Hypoplastic myelodysplasia may mimic aplastic anemia. A number of findings can help in distinguishing the two conditions.


Findings that are unreliable for distinguishing the two conditions:

(1) dyserythropoiesis

(2) collections of immature granulocyte cells (may be seen in aplastic anemia during marrow recovery)


Findings that are associated with hypoplastic myelodysplasia may include:

(1) circulating blasts

(2) dysplasia of myeloid series

(3) dysplasia of the megakaryocytes

(4) increased reticulin

(5) MDS-associated cytogenetic abnormalities


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