Any drug associated with withdrawal reactions in an adult can cause withdrawal in an infant. This includes paroxetine or other selective serotonin reuptake inhibitors (SSRIs).
Clinical features:
(1) The mother is taking an antidepressant during the third trimester of pregnancy and/or while breastfeeding.
(2) The neonate develops a discontinuation syndrome following delivery or if breastfeeding is interrupted.
(3) Other conditions that could explain the findings are excluded.
Features of the discontinuation syndrome may include:
(1) irritability or agitation
(2) tremors
(3) tachypnea and/or respiratory distress
(4) decerebrate posturing
(5) convulsions
(6) inconsolable crying
(7) problems eating
(8) problems sleeping
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