A patient who has been successfully vaccinated should show a rise in protective antibodies.
(1) concentration of protective antibody prior to vaccination
(2) concentration of protective antibody after vaccination
antibody response =
= (antibody concentration after) / (antibody concentration before)
• A “positive response” may vary but Kapetanovic et al used a ratio >= 2 as a positive response.
• A ratio < 1 might be a reason to double check the results (accuracy of the method for measuring the antibody concentration, specimen problem, etc).
To read more or access our algorithms and calculators, please log in or register.
Specialty: Infectious Diseases, Pharmacology, clinical