Antibiotic prophylaxis should be considered prior to vaginal delivery in certain women.
Heart conditions associated with a high risk of endocarditis:
(1) prosthetic cardiac valve
(2) prosthetic material used to repair a cardiac valve
(3) unrepaired cyanotic congenital heart disease
(4) palliated cyanotic congenital heart disease, including surgically reconstructed palliative conduits and shunts
• A history of infective endocarditis is not listed but would seem to be a significant risk factor.
Timing of first antibiotic dose: at the time of membrane rupture
Additional doses may be needed if there is a period of time between membrane rupture and vaginal delivery.
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Purpose: To identify a woman who should receive prophylactic antibiotics to prevent infective endocarditis prior to vaginal delivery.
Specialty: Infectious Diseases, Pharmacology, clinical
Objective: pharmacogenetics, prevention
ICD-10: I33, Z79.2,