Hemihyperplasia involves an asymmetric growth in the cranium, face, limbs, trunk and/or digits. Roubier developed a classification scheme based on the anatomic distribution of the enlargement. The abnormality may exist as an isolated defect or may be part of an underlying genetic disorder.


The differential diagnosis involves atrophy of a limb or other body part. In hemihyperplasia the smaller side is normal.


Affected Site


one side of the face


involvement of a single limb


involvement of at least one arm and one leg, which may be ipsilateral or contralateral



According to Rowe (1962) the criteria for hemifacial congenital hypertrophy are:

(1) unilateral enlargement of the viscerocranium (bounded superiorly by the frontal bone, inferiorly by the inferior border of the mandible, medially by the midline of the face, laterally by the ear; the pinna is included in the hypertrophic area but the eye is not).

(2) enlargement of all tissues (bone, teeth, soft tissue) within the affected area


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