Description

Vaitkus and Kussmaul developed an algorithm for distinguishing constrictive pericarditis and restrictive cardiomyopathy. The authors are from the University of Pennsylvania in Philadelphia.


Parameters:

(1) thickness of the pericardium on imaging studies

(2) number of hemodynamic criteria present

(3) availability of endomyocardial biopsy for detection of restrictive cardiomyopathy

 

Hemodynamic criteria for constrictive pericarditis:

(1) (left ventricular end diastolic pressure) - (right ventricular end diastolic pressure) <= 5 mm Hg

(2) right ventricular systolic pressure <= 50 mm Hg

(3) radio of (right ventricular end diastolic pressure) / (right ventricular systolic pressure >= 0.33

 

Thickness of Pericardium

Number of Hemo-dynamic Criteria

Probability of Constriction

thickened

1 to 3

high

thickened

0

indeterminate

not thickened

0 or 1

low

not thickened

2 or 3

indeterminate

 

Endomyocardial biopsy is performed if available for:

(1) indeterminate cases

(2) to confirm low probability of constrictive pericarditis

 

Surgery is performed:

(1) when there is a high probability of constrictive pericarditis

(2) when there is an indeterminate probability of constrictive pericarditis and endomyocardial biopsy is not available

(3) when there is an indeterminate probability of constrictive pericarditis and endomyocardial biopsy is negative for infiltrative cardiomyopathy

 

Medical therapy is given:

(1) when there is a low probability of constrictive pericarditis

(2) when there is an indeterminate probability of constrictive pericarditis and endomyocardial biopsy is positive for infiltrative cardiomyopathy


 


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