Description

Donovan and Starling developed an algorithm to aid in the management of a patient with asymptomatic mitral regurgitation. This can help determine the appropriate time to consider surgery.


 

Parameters:

(1) number of clinical factors

(2) left ventricular ejection fraction

(3) end systolic dimension of the left ventricle

(4) feasability of valve repair

 

Clinical factors:

(1) age in years

(2) mean pulmonary artery pressure

(3) cardiac index in liters per minute per square meter BSA

(4) left ventricular end-diastolic pressure in mm Hg

(5) coronary artery disease

(6) history of atrial arrhythmias

Clinical Factor

Finding

Points

age in years

<= 60 years of age

0

 

> 60 years of age

1

mean pulmonary artery pressure

<= 20 mm Hg

0

 

> 20 mm Hg

1

coronary artery disease

absent

0

 

present

1

cardiac index

> 2.0 liters per minute per sq m

0

 

<= 2.0 liters per min per sq m

1

left ventricular end diastolic pressure

<= 12 mm Hg

0

 

> 12 mm Hg

1

history of atrial arrhythmias

absent

0

 

present

1

 

number of clinical factors =

= SUM(points for all 6 factors)

 

Parameter

Finding

Points

number of clinical factors

0

0

 

1

1

 

>= 2

2

left ventricular ejection fraction

> 65%

0

 

60 - 65%

1

 

< 60%

2

left ventricular end systolic dimension in mm

< 40 mm

0

 

40 - 45 mm

1

 

> 45 mm

2

feasibility of valve repair

none

0

 

possible

1

 

definite

2

 

total decision points =

= SUM(points for the 4 parameters)

 

Interpretation:

• minimum total decision points: 0

• maximum total decision points: 8

 

Total Points

Management Recommendation

0 or 1

clinical and echocardiographic followup every 6-12 months

2

clinical and echocardiographic followup at 6 months

>= 3

proceed with surgery

 


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