Algorithm of Bedossa and Poynard (METAVIR CSG) for Grading the Activity of Chronic Hepatitis C in a Liver Biopsy

Purpose: To grade the histologic activity in a liver biopsy taken from a patient with chronic hepatitis C using the algorithm from the METAVIR Cooperative Study Group.

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Evaluation

Are you evaluating a liver biopsy from a patient with chronic hepatitis C?

Yes

Is bridging necrosis present?

Yes

Select an appropriate answer for each histologic finding

Piecemeal necrosis

Lobular necrosis

Portal inflammation

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Score for piecemeal necrosis

Score for lobular necrosis

Score for portal inflammation

Score for bridging necrosis

Histologic activity based on piecemeal and lobular necrosis

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Clinical Diagnosis, Including Family History For Genetics
Laboratory Tests
Other Testing
Criteria For Diagnosis
Severity, Prognosis, Stage
- Discriminant Score of Bonacini et al for Predicting Cirrhosis in a Patient with Chronic Viral Hepatitis C
- Grading and Staging Chronic Hepatitis in Liver Biopsy
Complications
- Criteria of Schoeniger-Hekele and Mueller for Using CA19-9 and CA125 to Diagnose Severe Liver Fibrosis in a Pateint with Noncholestatic Liver Disease

Therapy

Selection

Monitoring

Disease Progression

Specialty

Gastroenterology
Infectious Diseases

Objective

severity
prognosis
stage
disease progression

ICD-10

K74 - Fibrosis and cirrhosis of liver
B18.2 - Chronic viral hepatitis C

Info

Purpose: To grade the histologic activity in a liver biopsy taken from a patient with chronic hepatitis C using the algorithm from the METAVIR Cooperative Study Group.

Specialty: Gastroenterology, Infectious Diseases

Objective: severity, prognosis, stage, disease progression

ICD-10: K74, B18.2,

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