An increase in the urinary excretion of albumin is seen in diabetic nephropathy. One measure of this is the albumin excretion rate (AER).



(1) urine albumin concentration in mg/dL

(2) volume of urine in mL

(3) duration of specimen collection, up to 24 hours


duration of specimen collection in minutes =

= (collection period in hours) * 60


urine albumin excretion in µg =

= (urine albumin concentration in mg/dL) * (urine volume in mL) / 100 * 1000


albumin excretion rate in µg/min =

= (urine albumin excretion in µg) / (duration of collection period in minutes)

Albumin Excretion Rate (AER)


> 5 µg/min

early elevation of AER

>= 20 and < 200 µg/min in 2 or 3 of 3 timed specimens


>= 200 µg/min



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