Sometimes platelets show few or no granules.
Testing: Romanowsky peripheral blood smear
percent agranular or hypogranular platelets =
= (number of agranular or hypogranular) / (total platelets counted) * 100%
5 to 25%
25.1 to 50%
50.1 to 75%
Pathologic agranular/hypogranular platelets can be seen with::
(2) myeloproliferative disorder
(4) gray platelet syndrome (alpha storage pool disease)
(1) cytoplasmic fragments of leukemia cells (pseudothrombocyte)
(2) in vitro artifact (degranulation)
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Specialty: Hematology Oncology, Clinical Laboratory